Heat shock proteins hsps are overexpressed in a wide range of human cancers and are implicated in tumor cell proliferation differentiation invasion metastasis death and recognition by the immune system we review the current status of the role of hsp expression in cancer with special emphasis . Heat shock proteins hsps constitute a large family of proteins involved in protein folding and maturation whose expression is induced by heat shock or other stressors the major groups are classified based on their molecular weights and include hsp27 hsp40 hsp60 hsp70 hsp90 and large hsps. Chester medical school highlights the importance of heat shock proteins hsps in cancer cells and how we might utilise them therapeutically heat shock proteins hsps were originally identified as heat inducible gene products that had a role in cell survival. Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy these proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery however new drugs have recently been developed particularly
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